Compound overview

GHK-Cu: a copper tripeptide research overview

GHK-Cu is a naturally occurring copper-binding tripeptide. Its concentration in human plasma declines with age, which has made it a long-standing subject of dermal and extracellular-matrix research.

Copper coordination

The tripeptide binds a copper ion, and this copper complex is the form studied in most of the literature.

Dermal and structural-protein research

GHK-Cu is studied in dermal fibroblast models in connection with structural proteins, and is widely referenced across extracellular-matrix research.

Gene-expression studies

It is reported to modulate the expression of a large number of human genes in dermal tissue, and appears in cell-signalling and inflammatory-pathway research.

This overview is provided for educational and laboratory-research purposes only. It summarises published research and proposed mechanisms; it is not medical advice and does not describe or recommend human or veterinary use. Products are supplied strictly for laboratory research use only — not for human or veterinary consumption, and not a drug, food or cosmetic.